Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,911
R&D Systems™ AZD 5582 dihydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Dimeric Smac mimetic; potent IAP inhibitor
| Inhibitors | AZD 5582 dihydrochloride |
|---|---|
| Product Type | AZD 5582 dihydrochloride |
| Molecular Weight (g/mol) | 1088.21 |
| Purity | >97% |
2,912
R&D Systems™ Ryanodine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 15662-33-6 Molecular Formula: C25H35NO9
| CAS | 15662-33-6 |
|---|---|
| Molecular Formula | C25H35NO9 |
2,913
R&D Systems™ Selpercatinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective RET inhibitor
| Target | Ret |
|---|---|
| CAS | 2152628-33-4 |
| Purity | 0.98 |
| Chemical Name or Material | 6-(2-Hydroxy-2-methylpropoxy)-4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1 ]hept-3-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C29H31N7O3 |
2,914
R&D Systems™ Lenalidomide 4'-alkylC5-azide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Cereblon ligand with alkyl linker and terminal azide for onward chemistry
2,915
R&D Systems™ UCB 35625
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 202796-42-7 Molecular Formula: C30H37Cl2IN2O2
| CAS | 202796-42-7 |
|---|---|
| Molecular Formula | C30H37Cl2IN2O2 |
2,916
R&D Systems™ AGN 193109
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. High affinity pan-RAR antagonist
2,917
R&D Systems™ GlyH 101
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Reversible, voltage-dependent CFTR chloride channel blocker
| CAS | 328541-79-3 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | GlyH 101 |
| Recommended Storage | Store at -20°C |
| Synonym | N-2-Naphthalenyl-2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]glycine hydrazide |
| Molecular Formula | C19H15Br2N3O3 |
| Formula Weight | 493.15 |
2,918
R&D Systems™ iCRT 14
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 677331-12-3 Molecular Formula: C21H17N3O2S
| CAS | 677331-12-3 |
|---|---|
| Molecular Formula | C21H17N3O2S |
2,919
R&D Systems™ 17-AAG
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 75747-14-7 Molecular Formula: C31H43N3O8
| CAS | 75747-14-7 |
|---|---|
| Molecular Formula | C31H43N3O8 |
2,920
R&D Systems™ SDZ NKT 343
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Highly selective, human NK1 antagonist
2,921
R&D Systems™ PF 915275
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 857290-04-1 Molecular Formula: C18H14N4O2S
| CAS | 857290-04-1 |
|---|---|
| Molecular Formula | C18H14N4O2S |
2,922
R&D Systems™ Propidium iodide
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A Tocris product, part of R&D Systems. Red-fluorescent DNA stain; membrane impermeant to live cells. Pi staining differentiates live and dead cells
2,923
R&D Systems™ AZ 191
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A Tocris product, part of R&D Systems. Potent DYRK1B inhibitor
| CAS | 1594092-37-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | AZ 191 |
| Recommended Storage | Store at -20°C |
| Synonym | N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine |
| Molecular Formula | C24H27N7O |
| Formula Weight | 429.52 |
2,924
R&D Systems™ Nicotinamide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 98-92-0 Molecular Formula: C6H6N2O
| CAS | 98-92-0 |
|---|---|
| Molecular Formula | C6H6N2O |
2,925
R&D Systems™ Bax channel blocker
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Allosteric inhibitor of Bax channel activation
| Inhibitors | Bax channel blocker |
|---|---|
| Product Type | Bax channel blocker |
| Molecular Weight (g/mol) | 540.12 |
| Purity | >98% |